Preclinical investigations towards the first spacer gel application in prostate cancer treatment during particle therapy at HIT

Table 1 Treatment plan specification used for ¹² C and proton high dose irradiation

	¹²C	Protons
Prescribed RBE weighted dose	100 Gy (RBE)	100 Gy (RBE)
RBE	3	1.1
Absorbed target dose	33 Gy	91 Gy
*Target field dimensions() X/Y/Z [mm]**
Augmenix sample	25/65/25	25/65/25
*Target field dimensions() X/Y/Z [mm]**
HIT sample	32/55/40	-
Beam spot FWHM	6 mm	12 mm

The target fields in the irradiation plans were designed using safety margins around the target in order to guarantee complete coverage of the sample with the prescribed dose distribution. (*) Dimensions are defined in the beam coordinate system (c.f., Figure 2).

ISSN: 1748-717X