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Table 3 Subsequent recurrence after treatment for loco-regional recurrence in breast cancer

From: Radiation dose escalation for loco-regional recurrence of breast cancer after mastectomy

   Dose (Gy)
  All patents <66 ≥66
  n % n % n %
Number of patients 28 100.0% 12 42.9% 16 57.1%
Site       
 In Field 25 89.3% 10 35.7% 15 53.6%
 Field margin 3 10.7% 2 7.1% 1 3.6%
 Chest Wall 19 67.9% 8 28.6% 11 39.3%
 Sternum 2 7.1% 1 3.6% 1 3.6%
 Axilla 6 21.4% 4 14.3% 2 7.1%
 Supraclav fossa 6 21.4% 2 7.1% 4 14.3%
 Reconstructed breast 3 10.7% 1 3.6% 2 7.1%
 Internal Mammary 1 3.6% 1 3.6% 0 0.0%
 Infraclav fossa 1 3.6% 0 0.0% 1 3.6%
Progression during XRT 2 7.1% 1 3.6% 1 3.6%
  1. No difference was found between escalated (≥66) and standard (<66) dose groups in number or site of recurrences. Six patients had synchronous loco-regional recurrences. All recurrences were either in field or at the field margin. The sum of the anatomic sites exceeds 100% to account for simultaneous recurrences.