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Table 2 Univariate analysis of the effect of adjuvant radiotherapy (RT) and other variables on local relapse, distant relapse, disease-free survival and overall survival

From: Postoperative radiotherapy improves local control and survival in patients with uterine leiomyosarcoma

Variables

Local relapse

Distant relapse

Disease-free survival

Overall survival

HR

HR

HR

HR

(95% CI, p-Value)

(95% CI, p-Value)

(95% CI, p-Value)

(95% CI, p-Value)

RT (RT vs. No RT)

0.3

1.6

0.7

0.5

(0.1–0.8, 0.019)

(0.9–3.0, 0.12)

(0.4–1.1, 0.11)

(0.3–0.9, 0.028)

Margin (Positive vs. Negative)

4.6

NS

2.8

3.0

(2.0–10.7, 0.0004)

(1.5–5.0, 0.00082)

(1.6–5.7, 0.00061)

Size (≥9 cm vs. <9 cm)

3.0

2.6

2.9

3.6

(1.2–7.5, 0.021)

(1.4–4.9, 0.0023)

(1.6–5.1, 0.00023)

(1.8–6.9, 0.00016)

Age (>51 vs. ≤51)

NS

NS

NS

NS

FIGO 2008 Stage (II–IV vs. I)

2.7

2.3

3.1

3.6

(1.1–6.4, 0.025)

(1.3–4.3, 0.0048)

(1.7–5.3, <0.0001)

(1.8–6.9, 0.00019)

Adjuvant Chemo (Yes vs. No)

8.3

NS

4.2

6.9

(3.4–20.6, <0.0001)

(2.0–9.1, 0.0099)

(2.9–16.3, <0.0001)

Surgery Center (Community vs. Academic)

NS

NS

NS

NS

  1. Values HR (p-value).