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Table 2 Multivariate logistic regression analysis of various risk factors that might affect patients’ risk to develop severe fibrosis following radiotherapy

From: RETRACTED ARTICLE: SNPs in genes implicated in radiation response are associated with radiotoxicity and evoke roles as predictive and prognostic biomarkers

Risk factors

P value

ATM G/A rs1801516

0.55

HDM2 T/G rs2279744

0.03

HDM2 T/A rs1196333

0.03

TGFB1 C/T rs1800469

<0.01

XRCC1 G/A rs25487

<0.01

XRCC5 (Ku80) T/C rs1051677

0.42

Gender

0.79

Age at Radiotherapy

0.56

Total Radiation Dose

0.39

Chemotherapy

0.21

Follow Up

<0.01

Associated Diseases

0.48

  1. Significant associations are highlighted in bold.