Gene and SNP | Allele 1a | Allele 2b | Odds ratio | P-value | ||
---|---|---|---|---|---|---|
Cases | Controls | Cases | Controls | (95% CI) | ||
n (%) | n (%) | n (%) | n (%) | |||
CDKN1A C/A rs1801270 | 74 (77) | 157 (73) | 22 (23) | 57 (27) | 0.82 (0.47–1.44) | 0.49 |
TP53 G/C rs1042522 | 52 (54) | 112 (52) | 44 (46) | 102 (48) | 0.93 (0.57–1.51) | 0.76 |
TP53 C/T rs1800371 | 96 (100) | 213 (99.5) | 0 (0) | 1 (0.5) | NI | NI |
ATM G/A rs1801516 | 82 (85) | 202 (94) | 14 (15) | 12 (6) | 2.86 (1.18–6.48) | <0.01 |
HDM2 T/G rs2279744 | 71 (74) | 125 (58) | 25 (26) | 89 (42) | 0.49 (0.29–0.84) | <0.01 |
HDM2 T/A rs1196333 | 95 (99) | 198 (93) | 1 (1) | 16 (7) | 0.13 (0.02–0.99) | 0.02 |
TGFB1 G/A rs9282871 | 95 (99) | 213 (99.5) | 1 (1) | 1 (0.5) | NI | NI |
TGFB1 C/T rs1982073 | 40 (42) | 102 (48) | 56 (58) | 112 (52) | 1.28 (0.78–2.07) | 0.32 |
TGFB1 G/C rs1800471 | 92 (96) | 207 (97) | 4 (4) | 7 (3) | NI | NI |
TGFB1 C/T rs1800469 | 67 (70) | 122 (57) | 29 (30) | 92 (43) | 0.57 (0.34–0.96) | 0.03 |
TGFB1 G/A rs11466314 | 96 (100) | 213 (99.5) | 0 (0) | 1 (0.5) | NI | NI |
TGFB1 del rs8179182 | 94 (98) | 214 (100) | 2 (2) | 0 (0) | NI | NI |
TGFB1 C/T rs1800472 | 92 (96) | 199 (93) | 4 (4) | 15 (7) | 0.58 (0.19–1.79) | 0.33 |
TGFB1 C/T rs11466334 | 95 (99) | 213 (99.5) | 1 (1) | 1 (0.5) | NI | NI |
XRCC1 G/A rs25487 | 83 (86) | 155 (72) | 13 (14) | 59 (28) | 0.41 (0.21–0.79) | <0.01 |
XRCC1 C/T rs3213368 | 87 (91) | 193 (90) | 9 (9) | 21 (10) | 0.95 (0.42–2.16) | 0.90 |
XRCC1 G/A rs2139720 | 88 (92) | 190 (89) | 8 (8) | 24 (11) | 0.72 (0.31–1.67) | 0.44 |
XRCC1 C/T rs3213369 | 96 (100) | 213 (99.5) | 0 (0) | 1 (0.5) | NI | NI |
XRCC3 G/A rs861539 | 55 (57) | 133 (62) | 41 (43) | 81 (38) | 1.22 (0.75–1.99) | 0.42 |
XRCC3 A/C rs3212112 | 95 (99) | 213 (99.5) | 1 (1) | 1 (0.5) | NI | NI |
XRCC4 G/T rs3734091 | 95 (99) | 213 (99.5) | 1 (1) | 1 (0.5) | NI | NI |
XRCC5 A/G rs41296835 | 96 (100) | 213 (99.5) | 0 (0) | 1 (0.5) | NI | NI |
XRCC5 T/C rs1051677 | 89 (93) | 178 (83) | 7 (7) | 36 (17) | 0.39 (0.17–0.91) | 0.02 |
XRCC5 A/G rs1051685 | 85 (89) | 195 (91) | 11 (11) | 19 (9) | 1.33 (0.61–2.91) | 0.48 |
PRKDC T/C rs7830743 | 93 (97) | 197 (92) | 3 (3) | 17 (8) | 0.37 (0.11–1.31) | 0.11 |
LIG4 T/C rs1805384 | 90 (94) | 200 (93) | 6 (6) | 14 (7) | 0.95 (0.36–2.56) | 0.92 |
LIG4 C/T rs4987182 | 93 (97) | 209 (98) | 3 (3) | 5 (2) | NI | NI |
LIG4 C/T rs1805389 | 95 (99) | 206 (96) | 1 (1) | 8 (4) | NI | NI |
LIG4 C/T rs1805388 | 91 (95) | 195 (91) | 5 (5) | 19 (9) | 0.56 (0.20–1.56) | 0.26 |