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Table 5 Log-rank and proportional hazard analysis (Cox method) of progression-free survival (PFS) in relation to p53 codon 72 genotypes and pAkt protein expression

From: Expression of pAkt affects p53 codon 72 polymorphism-based prediction of response to radiotherapy in nasopharyngeal carcinoma

p53 codon 72 polymorphism

pAkt protein expression

Log-rank analysis

Cox-regression

  

Mean survival time(months)

p

HR

95% CI

p

G/G +G/C

Positive

24.66±2.38

—

1

reference

—

C/C

Positive

29.86±6.72

0.388

0.626

0.187-2.096

0.447

G/G +G/C

Negative

25.79±2.48

—

1

reference

—

C/C

Negative

40.60±2.04

0.034

0.034

0.00-5.394

0.191

  1. Note: p53 codon 72 G is equivalent to Arg and C is equivalent to Pro.