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Table 4 Multivariate analysis of progress-free survival (PFS) using the Cox proportional hazards model

From: Expression of pAkt affects p53 codon 72 polymorphism-based prediction of response to radiotherapy in nasopharyngeal carcinoma

Variables

Subgroups

HR

95%CI

p

T classification

T3-4 vs. T1-2

2.683

1.430-5.032

0.002

N classification

N+ vs. N0

1.778

1.196-2.644

0.004

p53 codon 72 genotype

C/C vs. G/C+G/G

0.300

0.092-0.983

0.047

p53 protein

Positive vs. Negative

1.714

0.893-3.291

0.105

pAkt protein

Positive vs. Negative

1.025

0.542-1.938

0.939

p21 protein

Positive vs. Negative

0.745

0.338-1.641

0.465

14-3-3σ protein

Positive vs. Negative

1.440

0.764-2.711

0.259

  1. Abbreviations: HR, hazard ratio; CI, confidence interval.
  2. Note: p53 codon72 G is equivalent to Arg and C is equivalent to Pro.