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Table 2 Clinical parameters in patients with or without an increase in Child-Pugh score ≥ 2

From: Dosimetric parameter predicting the deterioration of hepatic function after helical tomotherapy in patients with unresectable locally advanced hepatocellular carcinoma

  Without (n = 40) With (n = 32) pvalue
Gender    0.584
   Male 31 23
   Female 9 9
Age (years)    0.231
   median 62 59
   range 21-80 41-80
ECOG PS    0.910
   0 13 10
   1 27 22
Hepatitis    0.109
   No 0 2
   Yes 40 30
AFP (IU/mL)    0.094
   <400 30 18
   ≥400 10 14
LC    0.228
   No 11 5
   Yes 29 27
PVTT    *0.037
   No 21 9
   Yes 19 23
CP class    *0.006
   A 35 19
   B 5 13
AJCC stage    *0.021
   II 11 1
   III 26 27
   IVA 3 4
Previous treatment    0.374
   No 5 2
   Yes 35 30
Treatment after RT    0.394
   No 19 12
   Yes 21 20
  1. Abbreviations: ECOG PS Eastern Cooperative Oncology Group performance status; AFP alpha-fetoprotein; LC liver cirrhosis; PVTT portal vein tumor thrombosis; CP class Child-Pugh class; AJCC American Joint Committee on Cancer; RT radiotherapy.
  2. *Significant parameters in univariate analysis.