Figure 7

Effect of knockdown of miR-210 in combination with radiotherapy on apoptosis in human hepatoma xenograft. Apoptosis in tumors was analyzed by TUNEL staining. (a) TUNEL staining of tumor sections. A: control group; B: negative control vector group; C: radiotherapy group; D: anti-sense miR-210 therapy group; E: combined therapy group. The pictures are at 400× magnification. (b) Percentage of TUNEL-positive cells in stained tumor sections. Error bars indicate SEM (n = 9). * indicates p < 0.001 vs. control group; ^# indicates p < 0.001 vs. radiotherapy group; ^ indicates p < 0.001 vs. anti-sense miR-210 therapy group.