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Table 1 Patient baseline characteristics

From: Combination of peptide receptor radionuclide therapy with fractionated external beam radiotherapy for treatment of advanced symptomatic meningioma

Pat. no.

Age (y)

Sex

WHO grade

Karnofsky score

Meningioma location

Prior Resection

Prior RT

Mag3 Clearance (% of norm)

PTV (ml)

Indication for intensified protocol / clinical presentation

1

27

f

II

90

Right sphenoid wing

2

-

67.7

115

Large tumor, grade II, age/ pituitary insufficiency, decreased vision /ptosis

2

55

f

I

100

Both sphenoid wings

1

0

82.4

223

Very large tumor / retroorbital pressure,

3

68

f

NA*

90

Left petroclival

0

0

73.9

73

Critical location / Paresis of CN III, VI & VII

4

53

f

I

80

Right sphenoid wing

2

0

87.1

38

Critical location / exophthalmus and chemosis right eye, progressive loss of vision

5

52

f

I

100

Both sphenoid wings

1

0

61.7

197

Large tumor critical location /, progressive loss of vision

6

65

f

I

100

Right sphenoid wing

1

0

83.2

29.3

Critical location /trigeminal hypesthesia

7

62

f

I

80

Left falx & vertexregion

1

0

89.4

139

Clear-cell component, quickly progressive hemiparesis

8

63

m

II

90

Falx central region

1

1

112.7

28

Previous RT, Grade II, large tumor / paresis left leg

9

69

f

I

90

Left olfactory nerve & neurinoma of ethmoidal sinus§

1

0

82.9

121

Large tumor/ epilepsy, tremor

10

67

m

I

90

Multifocal bifrontal to right sphenoid wing

2

0

108.3

294

Ver large tumor/ dizziness, swelling and ptosis right palpebra

  1. * Biopsy not possible.
  2. § SSR-expression only in the meningioma, radiotherapy of both, meningioma and neurinoma.
  3. # Ga-DOTATOC.
  4. + Ga-DOTATATE.
  5. CN = Cranial Nerve.