Figure 2
From: Increased Artemis levels confer radioresistance to both high and low LET radiation exposures
High levels of Artemis increase the rate of γH2AX resolution in irradiated cells. Flow cytometry analysis of the distributions of cells with various γH2AX levels in HEK293 and 293Art cells following exposure to different qualities of ionizing radiation. Comparison of the distribution of γH2AX signal in control and irradiated cell populations at various times post exposure (left panels), including an enlarged graph of the irradiated samples (right panels) comparing control HEK293 (dashed lines) and 293Art (shaded). Measurements were taken 30 min after 2 Gy X-rays (A), 2 h after 2 Gy X-rays (B), 30 min after 2 Gy iron nuclei (C), and 2 h after 2 Gy iron nuclei exposure (D).