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Table 2 FDG and 64 Cu-ATSM PET uptake vs. Pimonidazole staining

From: 64Cu-ATSM and 18FDG PET uptake and 64Cu-ATSM autoradiography in spontaneous canine tumors: comparison with pimonidazole hypoxia immunohistochemistry

  Maximum pimonidazole labeled pixel value Mean pimonidazole positive area fraction
64Cu-ATSM Tmax/Mmean 3 h. 0.81 (p = 0.011) 0.69 (p = 0.043)
64Cu-ATSM Tmean/Mmean 3 h. 0.77 (p = 0.021) 0.56 (p = 0.126)
64Cu-ATSM Tmax/Mmean 24 h. 0.40 (p = 0.396) 0.036 (p = 0.964)
64Cu-ATSM Tmean/Mmean 24 h. 0.70 (p = 0.088) 0.24 (p = 0.595)
18FDG SUVmax 0.82 (p = 0.008) 0.79 (p = 0.014)
18FDG SUVmean 0.85 (p = 0.008) 0.77 (p = 0.017)
  1. Pimonidazole maximum labeled pixel value and mean pimonidazole positive area fraction of individual tumors correlated to their 64Cu-ATSM maximum and mean T/M ratios 3 and 24 h. pi. and 18FDG maximum and mean SUV. Spearman non-parametric correlation coefficients and p-value. Significant correlations in bold.