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Figure 1 | Radiation Oncology

Figure 1

From: 64Cu-ATSM and 18FDG PET uptake and 64Cu-ATSM autoradiography in spontaneous canine tumors: comparison with pimonidazole hypoxia immunohistochemistry

Figure 1

Pixel-by-pixel correlation. Methodology for pixel-by-pixel correlation analysis of pimonidazole immunostainings and 64Cu-ATSM autoradiography images. A, 100 × 100 μm pimonidazole image, with original ROI excluding folding and artifacts. B, 100 × 100 μm 64Cu-ATSM autoradiography image, identical ROI as image A. C, 64Cu-ATSM image rescaled from a pixel size of 100 × 100 μm to 1×1 mm, identical ROI as image A. D, new ROI applied with only pixels not transversed by the original ROI from image A included. Soft tissue sarcoma, displaying a weak insignificant correlation (rs = 0.30, p-value: 0.12) between the two modalities.

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