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Figure 4 | Radiation Oncology

Figure 4

From: Long-term outcome and toxicity of hypofractionated stereotactic body radiotherapy as a boost treatment for head and neck cancer: the importance of boost volume assessment

Figure 4

Left nasopharyngeal wall soft tissue necrosis and temporal lobe necrosis after SBRT. This patient was a 48-year-old male with type I NPC (T4N2M0) (a). He was treated with cisplatin-based concurrent chemoradiation via EBRT up to 70.2 Gy followed by SBRT at 21 Gy in 3 fractions due to persistent disease in the left skull base (b). Although he achieved CR and no loco-regional or distant metastasis occurred, left nasopharyngeal wall soft tissue necrosis (c) and temporal lobe necrosis (d) developed 4.4 and 7.2 months after SBRT, respectively. Temporal lobe necrosis and abscess formation, which might have arisen from adjacent nasopharyngeal soft tissue necrosis, were confirmed by surgical specimen pathology. He finally died 9.3 months after the SBRT treatment.

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