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Table 4 Salvage treatment for recurrent OCC following initial surgery

From: Follow up after IMRT in oral cavity cancer: update

Author [ref] Center Year Interval N recurrences after surgery alone IMRT OAS rate after salvage therapy
Surgery (+/−RT) RT (+/−CT)
Schwartz et al [8] U of Illinois, Chicago 2000 1956-1992 38 (28%) no ~25% at 5y (n = 27) 0% at 1y (n = 11)
Koo et al [9] Yonsei U, Seoul 2005 1991-2003 36/127 (28%) no ~25% at 5y (n = 13) 0% at 2y (n = 10)
Liu et al [10] U of Taiwan 2007 1995-2003 224 (na) no 34% at 5y (n = 326) 21% at 2y (n = 75)
Kokemueller et al [11] U of Hannover 2011 1980-2009 115/341 (37%) no ~25% at 5y (n = na) 10% at 4y (n = na)
own group U hospital of Zurich 2012 2002-2011 38 (na) yes 55% at 5y (n = 28) 30% at 5y (n = 10)
       75% at 5y (n = 18) 25% at 5y (n = 20)
  1. : outcome of recurrent OCC following surgery alone (n = 224) and surgery + RT/CT (n = 177).
  2. : results when analyzed according to ‘salvage IMRT for R0-1 situations’ versus ‘salvage IMRT for macroscopic disease’. U: University. na: not available.