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Table 6 Multivariate analysis for disease-free survival and overall survival

From: Concurrent radiochemotherapy in locally-regionally advanced oropharyngeal squamous cell carcinoma: analysis of treatment results and prognostic factors

Factors

Hazard ratio (95% CI)

DFS

OS

Performance status (ECOG)

(1 vs. 0)

1.20 (0.56-2.60)

p = 0.634

1.51 (0.59-3.86)

p = 0.395

Cigarette smoking

(current smokers vs. non-smokers)

0.93 (0.25-3.41)

p = 0.909

/

Alcohol consumption

(current drinkers vs. non-drinkers)

1.47 (0.59-3.63)

p = 0.399

1.17 (0.49-2.77)

p = 0.722

T stage

(T4 vs. T2-3)

0.70 (0.28-1.72)

p = 0.431

0.76 (0.29-2.02)

p = 0.582

N stage

(N2-3 vs. N0-1)

0.62 (0.22-1.74)

p = 0.362

1.10 (0.30-4.11)

p = 0.887

Overall stage

(IVA-B vs. III)

8.40 (2.11-33.47)

p = 0.003

3.82 (0.73-19.97)

p = 0.112

Haemoglobin level

≤ 12.5 g/dL vs. > 12.5 g/dL

0.28 (0.13-0.61)

p = 0.002

0.24 (0.10-0.60)

p = 0.002

  1. 95% CI, 95% confidence interval; DFS, disease-free survival; OS, overall survival; ECOG, Eastern Cooperative Oncology Group.