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Table 5 Multivariate analysis for local relapse-free survival, regional relapse-free survival and locoregional relapse-free survival

From: Concurrent radiochemotherapy in locally-regionally advanced oropharyngeal squamous cell carcinoma: analysis of treatment results and prognostic factors

Factors Hazard ratio (95% CI)
LRFS RRFS LRRFS
Performance status (ECOG)
(1 vs. 0)
1.11 (0.48-2.55)
p = 0.806
0.67 (0.25-1.82)
p = 0.431
1.12 (0.50-2.54)
p = 0.779
Cigarette smoking
(current smokers vs. non-smokers)
/ 3.98 (0.42-37.89)
p = 0.229
0.61 (0.15-2.45)
p = 0.485
Alcohol consumption
(current drinkers vs. non-drinkers)
1.35 (0.57-3.20)
p = 0.503
0.81 (0.25-2.63)
p = 0.723
1.71 (0.61-4.84)
p = 0.308
T stage
(T4 vs. T2-3)
/ / 0.58 (0.22-1.52)
p = 0.265
N stage
(N2-3 vs. N0-1)
1.13 (0.44-2.89)
p = 0.803
7.68 (1.02-58.05)
p = 0.048
0.73 (0.23-2.25)
p = 0.577
Overall stage
(IVA-B vs. III)
4.49 (1.24-16.27)
p = 0.022
3.57 (0.21-60.76)
p = 0.379
9.91 (2.16-45.42)
p = 0.003
Haemoglobin level
≤ 12.5 g/dL vs. > 12.5 g/dL
0.26 (0.11-0.62)
p = 0.002
0.27 (0.09-0.82)
p = 0.021
0.24 (0.10-0.57)
p = 0.001
  1. 95% CI, 95% confidence interval; LRFS, local relapse-free survival; RRFS, regional relapse-free survival; LRRFS, locoregional relapse-free survival; ECOG, Eastern Cooperative Oncology Group.