Table 5 Multivariate analysis for local relapse-free survival, regional relapse-free survival and locoregional relapse-free survival

Performance status (ECOG)

(1 vs. 0)

1.11 (0.48-2.55)

p = 0.806

0.67 (0.25-1.82)

p = 0.431

1.12 (0.50-2.54)

p = 0.779

Cigarette smoking

(current smokers vs. non-smokers)

/

3.98 (0.42-37.89)

p = 0.229

0.61 (0.15-2.45)

p = 0.485

Alcohol consumption

(current drinkers vs. non-drinkers)

1.35 (0.57-3.20)

p = 0.503

0.81 (0.25-2.63)

p = 0.723

1.71 (0.61-4.84)

p = 0.308

T stage

(T4 vs. T2-3)

/

/

0.58 (0.22-1.52)

p = 0.265

N stage

(N2-3 vs. N0-1)

1.13 (0.44-2.89)

p = 0.803

7.68 (1.02-58.05)

p = 0.048

0.73 (0.23-2.25)

p = 0.577

Overall stage

(IVA-B vs. III)

4.49 (1.24-16.27)

p = 0.022

3.57 (0.21-60.76)

p = 0.379

9.91 (2.16-45.42)

p = 0.003

Haemoglobin level

≤ 12.5 g/dL vs. > 12.5 g/dL

0.26 (0.11-0.62)

p = 0.002

0.27 (0.09-0.82)

p = 0.021

0.24 (0.10-0.57)

p = 0.001