Table 5 Multivariate analysis for local relapse-free survival, regional relapse-free survival and locoregional relapse-free survival
| Factors | Hazard ratio (95% CI) | ||
|---|---|---|---|
| LRFS | RRFS | LRRFS | |
|
Performance status (ECOG) (1 vs. 0) |
1.11 (0.48-2.55) p = 0.806 |
0.67 (0.25-1.82) p = 0.431 |
1.12 (0.50-2.54) p = 0.779 |
|
Cigarette smoking (current smokers vs. non-smokers) | / |
3.98 (0.42-37.89) p = 0.229 |
0.61 (0.15-2.45) p = 0.485 |
|
Alcohol consumption (current drinkers vs. non-drinkers) |
1.35 (0.57-3.20) p = 0.503 |
0.81 (0.25-2.63) p = 0.723 |
1.71 (0.61-4.84) p = 0.308 |
|
T stage (T4 vs. T2-3) | / | / |
0.58 (0.22-1.52) p = 0.265 |
|
N stage (N2-3 vs. N0-1) |
1.13 (0.44-2.89) p = 0.803 |
7.68 (1.02-58.05) p = 0.048 |
0.73 (0.23-2.25) p = 0.577 |
|
Overall stage (IVA-B vs. III) |
4.49 (1.24-16.27) p = 0.022 |
3.57 (0.21-60.76) p = 0.379 |
9.91 (2.16-45.42) p = 0.003 |
|
Haemoglobin level ≤ 12.5 g/dL vs. > 12.5 g/dL |
0.26 (0.11-0.62) p = 0.002 |
0.27 (0.09-0.82) p = 0.021 |
0.24 (0.10-0.57) p = 0.001 |