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Table 4 Univariate analysis correlating prognostic factors with disease-free and overall survival

From: Concurrent radiochemotherapy in locally-regionally advanced oropharyngeal squamous cell carcinoma: analysis of treatment results and prognostic factors

Factor   DFS OS
n 2 years
%
p-value 2 years
%
p-value
Gender
Male 59 25.9 0,0711 45.4 0,1789
Female 6 83.4   83.3  
Age (years)
≤ 50 20 27.8 0,8528 52.5 0,9873
> 50 45 34.7   49.8  
Performance status (ECOG)
0 44 46.5 <0.0001 65.9 <0.0001
1 21 0   11.6  
Cigarette smoking
Non-smokers 11 72.2 0,0323 72.8 0,1421
Current smokers 54 23.8   43.4  
Alcohol consumption
Non-drinkers 25 56.5 0,0080 65.9 0,0333
Current drinkers 40 19.1   39.7  
Subsite
Tonsil 36 29.3 0,4396 53.4 0,3679
Base of tongue 21 41.8   47.2  
Soft palate 6 0   50.3  
Posterior pharyngeal wall 2 0   0  
T stage
T2-3 47 43.4 0,0033 57.2 0,0455
T4 18 0   39.7  
N stage
N0-1 34 50.9 0.0004 73.4 0.0004
N2-3 31 14.1   26.6  
Overall stage
III 23 70.3 <0.0001 80.3 0.0006
IVA-B 42 12.2   30.8  
Histological differentiation
Well 22 40.9 0,1056 51.6 0,1287
Moderate 25 41.6   63.4  
Poor 18 10.3   32.2  
Haemoglobin level
≤ 12.5 g/dL 20 14.7 <0.0001 19.7 <0.0001
> 12.5 g/dL 45 41.6   63.8  
  1. n, number of patients; DFS, disease-free survival; OS, overall survival; ECOG, Eastern Cooperative Oncology Group.