Table 4 Univariate analysis correlating prognostic factors with disease-free and overall survival

Gender

Male

59

25.9

0,0711

45.4

0,1789

Female

6

83.4

83.3

Age (years)

≤ 50

20

27.8

0,8528

52.5

0,9873

> 50

45

34.7

49.8

Performance status (ECOG)

0

44

46.5

<0.0001

65.9

<0.0001

1

21

0

11.6

Cigarette smoking

Non-smokers

11

72.2

0,0323

72.8

0,1421

Current smokers

54

23.8

43.4

Alcohol consumption

Non-drinkers

25

56.5

0,0080

65.9

0,0333

Current drinkers

40

19.1

39.7

Subsite

Tonsil

36

29.3

0,4396

53.4

0,3679

Base of tongue

21

41.8

47.2

Soft palate

6

0

50.3

Posterior pharyngeal wall

2

0

0

T stage

T2-3

47

43.4

0,0033

57.2

0,0455

T4

18

0

39.7

N stage

N0-1

34

50.9

0.0004

73.4

0.0004

N2-3

31

14.1

26.6

Overall stage

III

23

70.3

<0.0001

80.3

0.0006

IVA-B

42

12.2

30.8

Histological differentiation

Well

22

40.9

0,1056

51.6

0,1287

Moderate

25

41.6

63.4

Poor

18

10.3

32.2

Haemoglobin level

≤ 12.5 g/dL

20

14.7

<0.0001

19.7

<0.0001

> 12.5 g/dL

45

41.6

63.8