Table 3 Univariate analysis correlating prognostic factors with disease control above clavicles

Gender

 Male

59

45.2

0,2713

52.3

0,0527

36.2

0,1562

 Female

6

83.0

100.0

83.3

Age (years)

 ≤ 50

20

49.3

0,7046

42.3

0,3524

30.7

0,6735

 > 50

45

48.2

63.2

44.8

Performance status (ECOG)

 0

44

62.8

0,0004

68.3

0,0169

54.7

0,0004

 1

21

19.2

20.8

9.8

Cigarette smoking

 Non-smokers

11

77.7

0,1651

89.8

0,0365

79.9

0,0475

 Current smokers

54

43.2

49.8

33.8

Alcohol consumption

 Non-drinkers

25

71.8

0,0163

75.3

0,0222

64.7

0,0094

 Current drinkers

40

34.8

47.2

27.2

Subsite

 Tonsil

36

42.8

0,3656

58.7

0,7991

37.8

0.4509

 Base of tongue

21

66.7

54.7

45.9

 Soft palate

6

49.2

50.2

50.9

 Posterior pharyngeal wall

2

0

0

0

T stage

 T2-3

47

54.0

0,1094

58.8

0,9960

49.1

0,0451

 T4

18

35.4

48.1

21.6

N stage

 N0-1

34

68.8

0.0006

93.8

<0.0001

66.6

<0.0001

 N2-3

31

28.3

22.2

16.4

Overall stage

 III

23

81.7

0.0002

95.3

<0.0001

81.6

<0.0001

 IVA-B

42

30.8

33.2

19.1

Histological differentiation

 Well

22

57.2

0,1931

59.2

0,1385

44.1

0,2296

 Moderate

25

54.3

76.3

54.7

 Poor

18

31.8

36.3

23.4

Haemoglobin level

 ≤ 12.5 g/dL

20

21.3

<0.0001

44.2

0,0046

19.0

<0.0001

 > 12.5 g/dL

45

60.1

65.8

51.5