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Table 3 Rectum RTOG, Anterior Rectal Wall RTOG, Rectum Partial, Anterior Rectal Wall Partial DVH Analysis and Univariate Associations with Grade ≥ 2 GI Toxicities

From: Acute gastrointestinal and genitourinary toxicity of image-guided intensity modulated radiation therapy for prostate cancer using a daily water-filled endorectal balloon

Grade ≥ 2 Combined GI/rectal

Rectum

Infield Rectum

Anterior Rectal Wall

Infield Anterior Rectal Wall

 

Mean ± SD

P value

Mean ± SD

P value

Mean ± SD

P value

Mean ± SD

P value

Volume (cm3)

167.1 ± 31.4

0.57

131.5 ± 25.3

0.59

26.9 ± 5.7

0.63

20.7 ± 4.6

0.54

Dmin (Gy)

4.2 ± 3.7

0.64

12.3 ± 4.6

0.08

5.8 ± 5.8

0.87

20.6 ± 7.3

0.17

Dmax (Gy)

81.8 ± 1.7

0.44

81.8 ± 1.7

0.44

81.8 ± 1.7

0.40

81.8 ± 1.7

0.40

Dmean (Gy)

36.0 ± 5.1

0.28

42.1 ± 4.1

0.04

54.2 ± 7.1

0.82

64.6 ± 3.1

0.48

Dmedian (Gy)

31.7 ± 5.9

0.09

35.9 ± 5.2

0.03

60.5 ± 8.7

0.91

70.9 ± 4.4

0.73

V10 (%)

87.4 ± 10.4

0.99

99.3 ± 2.1

0.64

88.6 ± 10.1

0.81

99.9 ± 0.3

NA

V20 (%)

77.1 ± 14.5

0.46

91.5 ± 11.6

0.21

84.7 ±11.2

0.92

99.6 ± 1.3

0.39

V30 (%)

57.1 ± 14.5

0.08

69.2 ± 15.3

0.02

80.8 ± 11.5

0.79

97.6 ± 3.4

0.30

V40 (%)

35.4 ± 7.6

0.13

43.4 ± 8.4

0.046

72.8 ± 11.5

0.76

89.6 ± 6.0

0.35

V50 (%)

24.2 ± 4.5

0.53

29.9 ± 4.8

0.24

62.1 ± 10.4

0.95

77.5 ± 7.2

0.90

V60 (%)

17.0 ± 3.0

0.85

21.3 ± 3.3

0.48

51.8 ± 9.2

0.91

65.6 ± 7.2

0.96

V65 (%)

14.0 ± 2.5

0.87

17.5 ± 2.9

0.51

46.6 ± 8.5

0.98

59.3 ± 7.1

0.81

V70 (%)

10.9 ± 2.2

0.86

13.7 ± 2.7

0.54

40.8 ± 8.1

0.95

52.2 ± 7.5

0.71

V75 (%)

7.2 ± 2.2

0.74

9.1 ± 2.7

0.55

32.2 ± 8.4

0.75

41.4 ± 9.4

0.58

V79.2 (%)

2.4 ± 2.1

0.49

3.0 ± 2.5

0.37

12.7 ± 9.8

0.42

16.4 ± 12.2

0.31

  1. Abbreviations: DVH = dose volume histogram; Dmin = minimum dose; Dmedian = median dose; Dmean = mean dose; Dmax = maximum dose; V10, V20, V30, V40, V50, V60, V65, V70, V75, V79.2 = volume receiving 10 Gy, 20 Gy, 30 Gy, 40 Gy, 50 Gy, 60 Gy, 65 Gy, 70 Gy, 75 Gy, 79.2 Gy, respectively.
  2. Note: The results are presented as mean ± standard deviation. The results listed as NA were not estimated due to the limited number of variations in the tested parameter.