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Table 3 Absolute DNA damage in %Tail DNA of fraction I-IV

From: Factors influencing heterogeneity of radiation-induced DNA-damage measured by the alkaline comet assay

n Fraction [Gy] Repair [min] %Tail DNA of five donors Mean %
     Donor1 Donor2 Donor3 Donor4 Donor5 Tail DNA
1 I 0 0 5.91 5.56 4.60 7.45 5.89 5.88
2 II 0 0 20.19 24.39 16.66 12.38 17.31 18.19
3 III 0 0 6.56 6.68 6.19 6.82 7.83 6.82
4 II 4 0 64.44 62.09 57.45 61.83 60.54 61.27
5 III 4 0 23.02 31.20 34.51 37.96 34.83 32.30
6 I 4 0 24.90 28.56 25.95 25.91 27.17 26.50
7 I 4 15 11.45 12.22 12.83 11.11 10.99 11.72
8 I 4 45 7.75 7.89 6.61 6.13 8.89 7.45
9 IV 2x4 0 30.05 29.58 31.94 25.88 29.27 29.34
10 IV 2x4 15 19.11 19.16 21.39 19.92 20.95 20.11
11 IV 2x4 45 12.02 11.45 9.79 15.54 12.90 12.34
  1. Mean DNA damage in %Tail DNA of donor leukocytes for fraction I-IV was represented*. The highest levels of basal and initial DNA damages (at 0 and 4 Gy) were detected for nucleoids without antioxidants or histones (fraction II).
  2. Abbreviations: n = number, Gy = Gray.
  3. * 200 leukocytes/sample of each donor were measured for calculation of DNA damage in %Tail DNA and variance. Mean variance was calculated from 5 donors.