| | |
Paired comparison
|
---|
Sample
|
%Tail DNA
|
SD
|
Compared pair
|
F-value
|
p-value
|
---|
0 Gy
|
6.2
|
7.6
| | | |
0 + 2 Gy
|
9.7
|
6.5
|
0 Gy / 0 + 2 Gy
|
24.03
|
<0.001
|
2 Gy
|
15.5
|
6.9
|
0 + 2 Gy / 2 Gy
|
74.31
|
<0.001
|
2 + 4 Gy
|
16.9
|
8.9
|
2 Gy / 2 + 4 Gy
|
3.220
|
0.073
|
4 Gy
|
20.7
|
8.1
|
2 + 4 Gy / 4 Gy
|
20.36
|
<0.001
|
4 + 8 Gy
|
30.1
|
12.3
|
4 Gy / 4 + 8 Gy
|
80.78
|
<0.001
|
8 Gy
|
43.1
|
14.4
|
4 + 8 Gy / 8 Gy
|
94.78
|
<0.001
|
- Leukocytes (200 leukocytes/sample of one donor) were irradiated with increasing doses (0-8 Gy) and mixed in equal proportions with the next higher irradiation dose level sample. Comparison of mean DNA damage in %Tail DNA for samples treated with 0, 2, 4 or 8 Gy and mixtures (0 and 2 Gy, 2 and 4 Gy, 4 and 8 Gy) revealed significant differences for almost all pairs and a trend for cells irradiated with 2 Gy vs. 2 + 4 Gy.
- Abbreviations: SD = standard deviation, p-value = probability value, F-value.