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Table 1

From: Proton and carbon ion radiotherapy for primary brain tumors delivered with active raster scanning at the Heidelberg Ion Therapy Center (HIT): early treatment results and study concepts

patient characteristics

  

[n]

[%]

patient number

33

100

gender

female

10

30.3

 

male

23

69.7

age at RT

 

[years]

 

median

42

 

range

7-77

  

[n]

[%]

pediatric patients [≤ 18 years]

3

9.1

histology

glioma

26

100

 

   WHO ° II

5

19.2

 

   WHO ° III

3

11.5

 

   WHO ° IV

18

69.2

 

meningioma

7

100

 

   WHO ° I

3

43

 

   WHO ° II

3

43

 

   WHO ° III

1

14

radiotherapy

mixed modality

22

66.6

 

   [12C] only

6

18.2

 

   [1H] only

5

15.2

particle reirradiation

7

21.2

  

[ml]

mean particle volume [particle only, ml]

65.64

mean particle volume [particle boost, ml]

69.29

mean photon volume [particle boost, ml]

252.65

  

[Gy]

range carbon total dose

18-45

range proton total dose

10-57.2

range photon total dose

50

  

[mm]

Tumor diameter before RT

29.7

Tumor diameter at first follow-up

27.1

Tumor diameter at second follow-up

24.9

  

[n]

[%]

relapse meningioma

0

0

relapse glioma WHO ° II

0

0

relapse glioma WHO ° III/° III

9

42.3