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Table 2 Apoptotic rates measured by the sub-G1 portion of flow cytometry in A549 and U373MG cells

From: DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity

   Control/drug 0 h 2 h 6 h 12 h 24 h
A549 IR 1.11 ± 0.93 1.55 ± 0.82 3.01 ± 1.93 1.72 ± 0.83 1.20 ± 0.99 1.03 ± 0.33
  PSA + IR 2.61 ± 1.05 1.53 ± 0.73 3.29 ± 1.71 8.02 ± 2.49 9.02 ± 3.20 7.72 ± 2.16
  IR 0.53 ± 0.10 1.23 ± 1.07 0.98 ± 0.37 0.70 ± 0.06 1.13 ± 0.88 0.89 ± 0.12
  DAC + IR 0.43 ± 0.10 1.20 ± 0.70 0.54 ± 0.02 0.57 ± 0.09 0.53 ± 0.07 1.05 ± 0.14
  IR 0.59 ± 0.16 0.94 ± 0.60 0.61 ± 0.15 0.86 ± 0.33 1.77 ± 0.66 1.66 ± 0.14
  ZEB + IR 0.84 ± 0.32 1.00 ± 0.61 0.97 ± 0.49 1.65 ± 0.52 1.62 ± 0.14 2.13 ± 0.05
U373MG IR 0.95 ± 0.10 0.61 ± 0.23 0.80 ± 0.18 0.71 ± 0.09 1.39 ± 0.20 1.68 ± 0.55
  PSA + IR 0.71 ± 0.19 0.67 ± 0.13 0.55 ± 0.06 0.63 ± 0.05 0.89 ± 0.16 1.57 ± 0.61
  IR 0.94 ± 0.05 0.64 ± 0.13 0.61 ± 0.05 0.64 ± 0.05 0.99 ± 0.20 1.68 ± 0.65
  DAC + IR 0.77 ± 0.04 0.83 ± 0.01 0.58 ± 0.05 0.81 ± 0.08 0.93 ± 0.12 1.45 ± 0.37
  IR 1.58 ± 0.25 1.39 ± 0.34 1.35 ± 0.01 1.12 ± 0.21 1.78 ± 0.34 2.33 ± 0.35
  ZEB + IR 0.95 ± 0.19 1.90 ± 1.21 2.14 ± 1.48 1.06 ± 0.01 1.28 ± 0.15 4.59 ± 1.23
  1. Abbreviations: IR = irradiation, PSA = psammplin A, DAC = 5-aza-2'-deoxycytidine, ZEB = zebularine