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Table 1 IC50 values for six DNMT inhibitors

From: DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity

Drugs Cell lines
  A549 U373MG
5-azacytine 3 uM 3 uM
5-aza-2'-deoxycytidine 300 nM 100 nM
Zebularine 800 uM ND*
Hydralazine 2 uM 20 uM
Epigallocatechin gallate 15 uM 5 uM
Psammaplin A 5 ug/ml 5 ug/ml
  1. *ND; not determined, IC50 value in U373MG, 800 uM, was used in subsequent experiments in A549 cells