Figure 3
From: Investigation of the interaction between the MIR-503 and CD40 genes in irradiated U937 cells
Suppression of CD40 expression by miR-503. (A) illustrates the miR-503 target sequence in the CD40 3'UTR that was predicted by Target Scan; (B) illustrates functional change of the cells transfected with the empty renilla luciferase reporter gene (psiCHECK2) or the reporter gene fused to the CD40 3' UTR. "+" represents transfection with a target gene and "-" no transfection. Results are expressed as relative light units (RLU) and were normalized with the luciferase activity expressed constitutively by the psiCHECK2 vector.