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Table 4 Toxicity Distribution

From: Accelerated hypofractionated radiation therapy compared to conventionally fractionated radiation therapy for the treatment of inoperable non-small cell lung cancer

Toxicity

Grade

ACRT

STRT1

STRT2

Total

p-value

  

(45 Gy)

(60-63 Gy)

(> 63 Gy)

  
  

n = 154

n = 99

n = 239

  

Esophagitis

0-1

107(89.9%)

80(88.9%)

82(90.1%)

269(89.7%)

0.958

 

≥ 2

12(10.1%)

10(11.1%)

9(9.9%)

31(10.3%)

 

Dysphagia

0-1

110(92.4%)

75(83.3%)

80(87.9%)

265(88.3%)

0.126

 

≥ 2

9(7.6%)

15(16.7%)

11(12.1%)

35(11.7%)

 

Pneumonitis

0-1

105(88.2%)

71(78.9%)

71(78.0%)

247(82.3%)

0.093

 

≥ 2

14(11.8%)

19(21.1%)

20(22.0%)

53(17.7%)

 

Radiation Dermatitis

0-1

117(98.3%)

79(87.8%)

78(85.7%)

274(91.3%)

0.002

 

≥ 2

2(1.7%)

11(12.2%)

13(14.3%)

26(8.7%)

 

Nausea/Vomiting

0-1

115(96.6%)

79(87.8%)

87(95.6%)

281(93.7%)

0.022

 

≥ 2

4(3.4%)

11(12.2%)

13(14.3%)

26(8.7%)

 

Weight loss

0-1

115(96.6%)

81(90.0%)

90(98.9%)

286(95.3%)

0.020

 

≥ 2

4(3.4%)

9(10.0%)

1(1.1%)

14(4.7%)