Figure 10

This picture shows a T3 tumour infiltrating the rectal wall and perirectal fat, with some irregular and heterogeneous lymph nodes within the mesorectum. After neo-adjuvant therapy there is an evident tumour regression without any invasion into the surrounding tissues as demonstrating by the gross specimen, where only a gelatinous mash has remained inside the rectal wall, and by the corresponding histological slice where any evidence of extraluminal infiltration is present anymore.