Fractionated stereotactic radiation therapy improves cranial neuropathies in patients with skull base meningiomas: a retrospective cohort study

Table 4 Example of very early visual acuity improvement during fractionated stereotactic radiation therapy course

Date	Visit reason	Time from start of RT (months)	Visual acuity left eye	Humphrey visual field (MSD/PD*) left eye
2/21/2006	Initial Consult	--	20/200+	−26.52/6.96
4/7/2006	On treatment (27 Gy)	0.6	20/100
4/12/2006	On treatment (32.4 Gy)	0.8	20/50
6/1/2006	Follow-up	2.4	20/30	−7.51/7.25
2/8/2007	Follow-up	11	20/25	−5.21/4.81
2/14/2008	Follow-up	23	20/25
11/18/2009	Follow-up	44	20/25	−5.76/7.60

*Mean standard deviation/Percent deviation.
Patient M.R. initially presented with left visual field deficits and decreased visual acuity in 1996 and underwent a subtotal resection of a left cavernous sinus meningioma with improvement. He had symptomatic worsening in 2005, and a radiographic evidence of progression in January 2006. He received FSRT from 3/20/2006 to 4/27/2006 reporting subjective improvement in vision in the third week of fractionated stereotactic radiation therapy, confirmed objectively on physical examination by Snellen chart using a near card. Objective improvement was also confirmed on Humphrey visual field testing. His vision remained excellent through last follow-up.

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