ERCC1 mRNA levels can predict the response to cisplatin-based concurrent chemoradiotherapy of locally advanced cervical squamous cell carcinoma

Table 1 Clinicopathological characteristics of the patients with LACSCC according to the ERCC1 mRNA levels

Characteristic	ERCC1 mRNA		P
	High level	Low level
Age, y
≤50	14	13
>50	15	18	0.622
Histologic grade
Well and moderately differentiated	12	19
Poorly differentiated	17	12	0.123
Tumor size, cm
≤4	8	12
>4	21	19	0.361
Parametrial invasion
No	14	15
Unilateral	12	11
Bilateral	3	5	0.774
Clinical lymph node involvement
N0	18	26
N1	11	5	0.056
FIGO stage
II	14	22
III	15	9	0.073
Hemoglobin levels at diagnosis, g/dL
≤11.3	8	5
>11.3	21	26	0.282
Platelets at diagnosis, ×10⁹/L
≤320	26	24
>320	3	7	0.204

Abbreviations: LACSCC locally advanced cervical squamous cell carcinomas, ERCC1 excision repair cross-complementation group 1, FIGO International Federation of Gynecology and Obstetrics.

ISSN: 1748-717X