Table 1 Patient, Tumor, and Treatment characteristics
Characteristic | All Patients (n,%) | Any Invasion |
|---|---|---|
Total | 87 (100) | 25 (29) |
Gender | Â | Â |
Male | 68 (78) | 19 (76) |
Female | 19 (22) | 6 (24) |
Age | Median = 57 years (range 33 – 81) | Median = 58 years (range 41 – 81) |
Ethnicity | Â | Â |
Caucasian/Other | 49 (56) | 13 (52) |
African-American | 38 (44) | 12 (48) |
KPS score | Â | Â |
50 - 80 | 73 (84) | 21 (84) |
90 - 100 | 14 (16) | 4 (16) |
Primary site with T-stage | Â | Â |
Larynx | 78 (90) | 21 (84) |
T3 | 44 (51) | 2 (8) |
T4a | 30 (34) | 18 (72) |
T4b | 4 (5) | 1 (4) |
Hypopharynx | 9 (10) | 4 (16) |
T4 | 8 (9) | 4(16) |
T4b | 1 (1) | 0 (0) |
N-stage | Â | Â |
N0 | 34 (39) | 11 (44) |
N1 | 11 (13) | 6 (24) |
N2 | 35 (40) | 5 (20) |
N3 | 7 (8) | 3 (12) |
Overall Stage | Â | Â |
III | 24 (28) | 1 (4) |
IVA | 53 (61) | 20 (80) |
IVB | 10 (11) | 4 (16) |
Concurrent Therapy | Â | Â |
None | 9 (10) | 2 (8) |
Cetuximab | 6 (7) | 1 (4) |
Cytotoxic Chemotherapy | 72 (83) | 22 (88) |
Neoadjuvant Chemotherapy | Â | Â |
No | 75 (86) | 21 (84) |
Yes | 12 (14) * | 4 (16) |
Fractionation of RT | Â | Â |
Conventional | 39 (45) | 9 (36) |
Altered Fractionation | 48 (55) | 16 (64) |
IMRT | Â | Â |
Yes | 52 (60) | 15 (60) |
No | 35 (40) | 10 (40) |
Local Recurrence | Â | Â |
Yes | 17 (20) | 7 (28) |
No | 70 (80) | 18 (72) |
Regional Recurrence | Â | Â |
Yes | 5 (6) | 1 (4) |
Synchronous with LR | 3 (60) | 1(100) |
Isolated | 2 (40) | 0 (0) |
No | 82 (94) | 24 (96) |
Distant Metastasis | Â | Â |
Yes | 16 (18) | 4 (16) |
No | 71 (82) | 21 (84) |