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Figure 4 | Radiation Oncology

Figure 4

From: Autophagy inhibition plays the synergetic killing roles with radiation in the multi-drug resistant SKVCR ovarian cancer cells

Figure 4

Effects of inhibitors for autophagy and apoptosis on the cell survival rate. (A) Dose-effect changes after radiation in SKVO3 cells with or without 3MA(2.5mM) and ZVAD(20μM). (B) Dose-effect changes after radiation in SKVCR cells with or without 3MA(2.5mM) and ZVAD(20μM). (C) SKOV3 cells were exposed to different radiation formulae (0Gy,1Gy×2×5,2Gy×5,10Gy×1) with or without 3MA (5mM) and ZVAD(20μM), cell viability was analyzed by CCK-8 assay. (D) SKVCR cells were exposed to different radiation formulae (0Gy,1Gy×2×5,2Gy×5,10Gy×1) cells with or without 3MA (5mM) and ZVAD(20μM), cell viability was analyzed by CCK-8 assay. *P<0.05, vs sham-irradiated. Results were expressed as the percentage of untreated cells, Mean ± SD of thrice. *P<0.05, vs untreated cell.

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Radiation Oncology

ISSN: 1748-717X

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