Table 2 OARs dosimetric endpoints of TD-3DCRT, TD-IMRT and FIF techniques for AWBRT

ISPILATERAL LUNG

V _5Gy (%)

TD-3DCRT

21.6 ± 5.3

TD-IMRT

18.7 ± 4.2

p < 0.01

FIF

22.4 ± 5.2

NS

V _10Gy (%)

TD-3DCRT

16.8 ± 4.6

TD-IMRT

13.9 ± 3.3

p < 0.01

FIF

15.8 ± 4.2

NS

V _20Gy (%)

TD-3DCRT

13.2 ± 4.1

TD-IMRT

9.9 ± 2.3

p < 0.001

FIF

11.7 ± 3.6

p < 0.05

MLD (Gy)

TD-3DCRT

6.9 ± 1.8

TD-IMRT

5.6 ± 1.1

p < 0.001

FIF

6.3 ± 1.5

NS

V _30Gy (%)*

TD-3DCRT

6.5 ± 2.3

TD-IMRT

6.9 ± 1.5

NS

FIF

7.3 ± 2.2

NS

V _40Gy (%)*

TD-3DCRT

5.3 ± 1.8

TD-IMRT

4.5 ± 1.2

NS

FIF

4.2 ± 1.8

p < 0.05

HEART

V _25Gy (%)

TD-3DCRT

5.5 ± 4.6

TD-IMRT

3.4 ± 3.1

p < 0.01

FIF

3.4 ± 3.6

p < 0.01

MHD (Gy)

TD-3DCRT

4.0 ± 2.2

TD-IMRT

3.0 ± 1.4

p < 0.05

FIF

3.0 ± 1.6

p < 0.01

CONTRALATERAL LUNG

D _0.1cc (Gy)

TD-3DCRT

1.8 ± 0.6

TD-IMRT

1.5 ± 0.5

p < 0.01

FIF

2.3 ± 0.9

p < 0.001

CONTRALATERAL BREAST

D _0.1cc (Gy)

TD-3DCRT

3.4 ± 1.9

TD-IMRT

2.3 ± 1.3

p < 0.05

FIF

4.3 ± 3.0

NS

D _mean (Gy)

TD-3DCRT

0.43 ± 0.09

TD-IMRT

0.38 ± 0.07

p < 0.05

FIF

0.52 ± 0.12

p < 0.001

Normal tissues external to PTV

D _2cc (%) ^{^}

TD-3DCRT

8.3 ± 2.3

TD-IMRT

5.0 ± 1.4

p < 0.001

FIF

4.4 ± 1.3

p < 0.001