Table 3 Upregulated networks with score ≥8 are presented

1

26sProteasome, ACHE, AChR, Akt, AQP4, BIN1, CAMK2A, CHRNA1, Creb,ERK1/2, FRZB, HSPA1L, IDE, ISL1, KCNC1, KIAA0368, KIF1B, MYOD1, MYOG, NES, NFkB (complex),NOL3, P2RY2, PDGF BB, PGK1, PLCG1, PPARGC1A, PRKCQ, RAPSN, RNF217, RXRG, S100B, SLC37A4, SNTA1, THPO

44

28

Cell Death, Neurological Disease, Cellular Development

2

ALDOA, ARPP21, ATP1A1, ATP1B1, ATP2A2, ATP6V0E2, BCL6, C15orf63, CIITA, ECSIT, FXYD4, Gapdh (includes others), Gm9790/Higd1a, GNAO1, HNRNPUL1, HSP90AB1, HTT, IL5, LDLR, NAA15, NDUFA12, PKM2, PMP22, POU3F1, RAB3A, RPH3A, SACS, SLC16A3, SPI1, SQSTM1, SYN2, TPI1, TRAF6, TUBA3C/TUBA3D, XBP1

21

17

Genetic Disorder, Neurological Disease, Skeletal and Muscular Disorders

3

ACTA1, ACTN1, AKAP6, ATP2B1, CDK16, CPE, ELL2, FSH, FYCO1, GK, GOT1, GPCPD1, IPO13, KIDINS220, LBX1, Lh, LIF, MAP1LC3B, NANOG, NOL3, PAX6, PCSK1N, PDE4D, PGK1, PHACTR2, PPFIA4, PPP2R5B, PRKAR1A, PRKAR2A, PSMD1, Ryr1l, SNAP23, STX3, TPM1 (includes EG:22003), VAMP8

19

16

Reproductive System Development and Function, Cellular Development, Cellular Growth and Proliferation

4

ABCC9, ALDOA, ATP1A1, CACNA1A, CACNA1B, CACNB1, CACNB4, CDH15, CTNNB1, DLG4, GOT2, HTT, IDH2, IL5, KCNJ11, KRAS, LDHA, LDHB, MYC, PCLO, PITX2, PRKCE, SCN1B, SCN2B, SLC25A4, SLC27A1, SYT1, SYT2, TP53, TPI1, TRIO, UGP2, VDAC1

16

14

Molecular Transport, Genetic Disorder, Carbohydrate Metabolism

5

AHR, APAF1, ATP1B2, BMI1, CAB39, CCNG1, CHEK2, CIITA, CREBBP, E2F6, ESRRG, Estrogen Receptor, HIST1H1A, Hist2h4 (includes others), HSP90AA1, MAPK12, MCM3, NFIC, Pcp4l1, PHC1, PLA2G12A, PRNP, RAD51AP1, Rb, RING1, SFTPC, SMARCA4, SMARCD3, STK11, STRADB, STUB1, Thymidine Kinase, TP53, TUBA8, UBE2B

16

14

Cell Cycle, Cell Death, Hematological System Development and Function

6

ATF3, B3GALT1,Calcineurin protein(s), Calmodulin, CCNA1, CIITA, CISH, CORO6, CREB1, CYP8B1, F2, FEM1A, GDF1, Gsk3, GSTA5, HSD17B7, HSPA8, IL1B, IL1R1, INSR, KCNQ5, Mapt, OPA3, PLCG1, PMS1, PPARGC1A, PSEN1, RORA, SATB1, SERPINA3, SIX1, SLC25A25, SOD1, TUBA4A, USP13

16

14

Cell Death, Neurological Disease, Tissue Morphology

7

ACSL1, APOA4, BCL2, CITED2, CPT1B, CRYAB, E2F1, EYA4, FOXC2, Fundc2, GSTA3, Ins1, ITGB6, KPNA3, Ldh, LEP, NEB, NEU2, NFKB1, PCSK1, POU2F1, PPARGC1A, PPP1R3A, PTGES, PTGS2, SOX6, SP1, SPTB, TMCC2, TNF, TNIK, TRAF2, TSPO, UCP3, ZFP36

16

14

Energy Production, Lipid Metabolism, Small Molecule Biochemistry

8

APOA4, ATF3, CD3, CD80, CD86, CEBPB, CIITA, COL1A1, COX5A, COX6B1, CPEB3, EFCAB6, ELAVL1, Gsk3, HELT, HSD11B1, HSPB2, IDH3B, IFNG, IL4, IL1RN, IRF1, NEIL2, NEUROG1, NR3C2, NRF1, POLR2A, Rac, TACC2, TCF7L2, TRAK1, TRAM2, USP2, VLDLR, WWP2

14

13

Cellular Growth and Proliferation, Hematological System Development and Function, Tissue Development

9

ACTA1, ACTC1, AGTR1, C14orf166, CUL5, DCT, DDX1, DMPK, DOT1L, EIF1AY, ENO1, ENPP4, FXR1, FXYD1, FZD9, Histone h3, HRASLS, JUN, MECP2, MLLT3, MYH1, MYH2, MYH4, PABPC4, RELN, SCNN1A, SGK1, STAU1, SYNCRIP, TCF4, THOC4, UCP1, UQCRC1, YWHAZ, YY1

14

13

Cellular Function and Maintenance, Molecular Transport, Cellular Assembly and Organization

10

ABHD5, ADAM12, ADCK3, ADM, CALCRL, CD40LG, DOK7, ENDOG, ERBB2, FILIP1, FLNA, G6pd2, GNB2L1, HIF1A, Hsp70, Hsp90, HSP90AA1, IGF1R, ITGB1, KDM3A, MUSK, NR3C1, NRG1 (includes EG:112400), PACSIN3, PAK1, PGM1, PLIN5, PRKCE, PSEN1, Rac, RAMP1, SRC, STUB1, TLN2, TTN

11

11

Cell Death, Cell-To-Cell Signaling and Interaction, Nervous System Development and Function

11

ADAM10, ADIPOR1, ADRA1B, CCND2, CCND3, COX7A1, CXCL10, CXCL12, CYP11A1, CYP7A1, DMD, DTNA, DUSP26, FSHB, HIPK3, HSF4, ITGB4, LCK, MAPK3, MAPRE3, MET, Mlc, NFKB2, NR5A1, PI3K (complex), PIN1, PITX1, PLEC, PRKCZ, RAC1, Ras, SOX9, SYNC, TCEA3, THRB

10

10

Cancer, Tissue Development, Embryonic Development

12

ABCB4, AGER, AIMP2, CD2, CD28, CD40, CD59, CD86, CD40LG, DISC1, DNM2, DYRK1B, FGFR1, GRB2, GRB14, HGF, IL2, IL12 (complex), JAK1, JAK2, MET, P38 MAPK, PDE4A, PDGFA, PDGFRB, PIK3C2B, PLCG1, PTPN2, ASA1, SH2B3, Sos, SQSTM1, WAS, ZAP70, ZFP106

8

9

Cellular Movement, Cell Death, Immune Cell Trafficking