Figure 5
From: Exposure to ionizing radiation induced persistent gene expression changes in mouse mammary gland
Upregulation of cellular proliferation and metabolic pathways involved in neoplasia. A) The third upregulated network involves reproductive system development and function, cellular development, cellular growth and proliferation and upregulation of at least one gene (LBX1) has been associated with cellular transformation. B) The fourth upregulated network involves molecular transport, genetic disorder, carbohydrate metabolism and at least 5 (ALDOA, LDHB, SLC16A3, TPI1, VDAC1) genes are related to carcinogenesis.