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Table 3 Characteristics and dose-volume parameters of the different dose calculations

From: Evaluation of heterogeneity dose distributions for Stereotactic Radiotherapy (SRT): comparison of commercially available Monte Carlo dose calculation with other algorithms

Structure Parameter SHM CCC SP MC CCC vs. SP CCC vs. MC SP vs. MC
   Mean (SD) Mean (SD) Mean (SD) Mean (SD) Mean [%] p-Value Mean [%] p-Value Mean [%] p-Value
  IC dose(Gy) 48.00 (0.0) 45.35 (1.3) 46.04 (1.4) 44.84 (1.1) 1.49 N.S. -1.14 N.S. -2.67 0.0036
  max dose(Gy) 52.17 (2.6) 49.12 (3.1) 48.45 (2.7) 48.10 (2.5) -1.38 N.S. -2.12 N.S. -0.73 N.S.
PTV PTV95(Gy) 44.92 (0.9) 40.53 (2.4) 41.42 (2.2) 39.68 (2.9) 2.15 N.S. -2.15 N.S. -4.39 0.033
  PTVmin 42.88 (1.8) 38.05 (3.0) 38.31 (3.0) 37.57 (2.3) 0.67 N.S. -1.28 N.S. -1.96 N.S.
ITV ITVmin 44.88 (1.4) 41.01 (2.2) 42.38 (2.2) 40.66 (1.8) 3.22 N.S. -0.86 N.S. -4.2 0.0094
Lung-ITV MLD(Gy) 5.72 (2.3) 5.28 (2.1) 5.31 (2.0) 5.33 (2.1) 0.61 N.S. 1.03 N.S. 0.42 N.S.
  V20(%) 9.18 (4.6) 8.22 (4.3) 8.44 (4.3) 8.54 (4.4) 2.55 N.S. 3.68 N.S. 1.16 N.S.
  V5(%) 28.21 (9.5) 27.57 (9.6) 27.85 (9.4) 28.03 (9.6) 1.02 N.S. 1.65 N.S. 0.63 N.S.
  HI 1.21 (0.09) 1.26 (0.09) 1.26 (0.10) 1.27 (0.07) -0.34 N.S. 0.48 N.S. 0.82 N.S.
  CI 2.69 (0.56) 2.71 (0.38) 2.92 (0.60) 2.86 (0.41) 7.19 N.S. 5.30 N.S. -2.04 N.S.
  1. N.S., not significant.
  2. Abbreviations: SHM, scatter homogeneous mode, CCC, C.C.Convolution, SP, Superposition, MC, Monte Carlo.
  3. PTV, planning target volume. ITV, internal target volume.
  4. HI, homogeneity index. CI, conformity index.