Table 2 Overview of miRNAs with significantly different levels of expression in rectal tumors of responders and non-responders to neoadjuvant chemoradiotherapy

miR-450b-5p

U

D

0.07

0.0003

RANBP9, SLC19A2, XIAP, RGMB, SMAD2, SERPINA5, SOX2, TCF5, TIMP2, TGFBR2

let-7e

U

D

0.48

0.0075

NRAS^#, KRAS^#, SOCS1^#, HMGA2^#, ABCC5, HOXD1, MASP1, ERCC6, IGF1

miR-450a

U

D

0.16

0,0104

MAP3K2, RAB31, TOPBP1, CREB1, DNMT3A, EGFR, ERCC5

miR-99a*

U

D

0,21

0,0163

RAD51C, RAD9B, TIAM1, TMEM87a, TMEM71, SOCS4, RANBP4, RANBP6

miR-190b

D

U

4.03

0.0290

CDKN1B, MUC17, MYCBP2, SMAD2, TCF4, CASP2, TP53INP1

miR-29b-2*

D

U

4.25

0.0375

AKT3, RANBP9, PARP2, HDAC5, CDKN3, AGR2, SLC19A2, FOXN3

miR-215

D

U

4.40

0.040

ZEB2^#, ALCAM^#, TYMS (TS) ^#, DHFR^#, EREG, HOXB9, NOD2

miR-196b

U

D

0.42

0,043

HOXB8^#, HOXC8^#, ERG^#, BACH1^#, FAS, TBRG1, TOX3