Table 1 Patient (n – 141) Characteristics and Univariate Analysis for Impact on Local Control
Characteristic | # of Patients(range or %) | p value |
|---|---|---|
Mean Age (yrs) at end of radiation | 67 (33–94) | 0.9055 |
Gender | Â | 0.3902 |
   male | 125 (88.7%) |  |
   female | 16 (11.3%) |  |
Race | Â | 0.1133 |
   Caucasian | 119 (84.4%) |  |
   Non-caucasian | 22 (15.6%) |  |
Median Pack Years | 44 (0–135) | 0.6769 |
Smoker | Â | 0.3530 |
   Never | 12 (8.5%) |  |
   Former | 92 (65.2%) |  |
   Current | 32 (22.7%) | 0.5568 |
   Unknown | 5 (3.5%) |  |
Heavy Alchohol Use | Â | 0.0630 |
   Never (Reference) | 89 (63.1%) |  |
   Former | 21 (14.9%) | 0.8836 |
   Current | 19 (13.5%) | 0.0222 |
   Unknown | 12 (8.5%) |  |
Ant Commissure | Â | 0.0505 |
   Involved | 71 (50.3%) |  |
   Non Involved | 52 (36.9%) |  |
   Unknown | 18 (12.8%) |  |
Tumor Bulk | Â | 0.6386 |
   Bulky | 55 ( 39%) |  |
   Non bulky | 86 ( 61%) |  |
Hemoglobin (g/dL) | 14.2 | Â |
Grade | Â | 0.6614 |
   Well (Reference) | 43 (30.5%) |  |
   Moderate | 57 (40.4%) | 0.7192 |
   Poor | 14 (10%) | 0.3646 |
   Unknown | 27 (19.1%) |  |
Stage (T2b vs T1a/b/2a) | Â | 0.0205 |
   1a | 65 ( 46%) | 0.0033 |
   1b | 21 (14.9%) | 0.1766 |
   2a | 29 (20.6%) | 0.0621 |
   2b (Reference) | 25 (17.7%) |  |
   Unknown | 1 (1%) |  |
Subglottic Ext | Â | 0.0505 |
   Yes | 18 (12.8%) |  |
   No | 96 (68.1%) |  |
   Missing | 27 (19.2%) |  |
Supraglottic Ext | Â | 0.4668 |
   Yes | 30 (21.2%) |  |
   No | 87 (61.7%) |  |
   Missing | 24 (17%) |  |
Median Overall Treatment Time (wks) | 6.5 (4–9.7) |  |
Radiation Dose (cGy) as Continous | 6820 (6300–7264) | 0.0367 |
   ≤66 Gy | 45 |  |
   > 66 Gy | 96 |  |
Median Dose/Fraction | 212 (176–256) | 0.1353 |
   ≤2Gy/fx | 45 (31.9%) |  |
   >2Gy/fx | 95 (67.4%) |  |
missing | 1 (1%) | Â |
Mean Follow-Up (month) | 67.7 (0–239) |  |