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Table 3 Total marrow irradiation: plan characteristics for Reg 2.5, Reg 5.0 (“regular” delivery with a 2.5 cm and 5.0 cm field width) and DJDC 5.0 (dynamic jaw/dynamic couch delivery with a 5.0 cm maximum field width)

From: Accelerated large volume irradiation with dynamic Jaw/Dynamic Couch Helical Tomotherapy

   Reg 2.5 Reg 5.0 DJDC 5.0
PTV D99 (Gy) 12.2 ± 0.6 11.9 ± 0.6 11.9 ± 0.3
  D1 (Gy) 19.6 ± 0.3 20.1 ± 0.4 19.6 ± 0.3
  CI 95 1.30 ± 0.15 1.7 ± 0.23 1.47 ± 0.05
  UI 1.27 ± 0.05 1.34 ± 0.08 1.31 ± 0.07
  TV95% 0.781 ± 0.074 0.768 ± 0.037 0.768 ± 0.057
bladder mean (Gy) 6.8 ± 1.3 8.2 ± 1.1 8.0 ± 1.8
small bowel mean (Gy) 6.8 ± 1.2 8.2 ± 1.1 7.2 ± 1.0
  D50 (Gy) 6.0 ± 0.9 8.1 ± 3.7 6.6 ± 1.0
esophagus mean (Gy) 6.7 ± 1.2 9.0 ± 0.5 7.2 ± 1.0
brain mean (Gy) 8.3 ± 0.6 8.1 ± 1.3 8.7 ± 1.6
  D50 (Gy) 6.9 ± 0.8 7.2 ± 1.7 8.1 ± 0.3
liver mean (Gy) 7.6 ± 0.4 8.3 ± 0.5 8.5 ± 0.6
lenses mean (Gy) 2.4 ± 0.2 2.5 ± 0.3 2.7 ± 0.3
right lung mean (Gy) 8.0 ± 0.2 8.2 ± 0.3 8.1 ± 0.1
  D50 (Gy) 6.2 ± 0.3 6.7 ± 0.3 6.6 ± 0.1
left lung mean (Gy) 8.0 ± 0.1 8.1 ± 0.3 8.1 ± 0.3
  D50 (Gy) 6.3 ± 0.1 6.7 ± 0.3 6.6 ± 0.1
stomach mean (Gy) 5.2 ± 0.8 6.6 ± 1.1 5.9 ± 0.7
kidneys mean (Gy) 6.1 ± 0.6 6.0 ± 0.8 7.1 ± 0.8
parotid glands mean (Gy) 4.2 ± 0.8 4.2 ± 0.9 5.8 ± 1.2
thyroid gland mean (Gy) 4.2 ± 0.5 4.9 ± 0.5 5.1 ± 0.5
integral dose (Gy x l) 631.9 ± 143.4 724.5 ± 140.6 690.0 ± 122.3
  1. Conformity was superior in Reg 2.5 compared to Reg 2.5 and DJDC 5.0 (bold print). Reg 2.5 slightly outperformed DJDC 5.0 in terms of liver, kidney, parotid gland and thyroid sparing and D50 to both lungs (bold print).