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Table 3 Odds Ratios for Choice of WBRT*alone versus SRS† Alone

From: Physician self-reported treatment of brain metastases according to patients’ clinical and demographic factors and physician practice setting

WBRT* vs. SRS

OR (95%CI) ††1

P

Lesions

  

1 (referent)

1.00

 

3

3.5 (2.7,4.4)

<.0001

8

59.8 (29.1,122.8)

<.0001

Age

  

55 (referent)

1.00

 

80

2.0 (1.5,2.6)

<.0001

Extracranial Disease

  

None (referent)

1.00

 

Active

5.5 (3.7,8.1)

<.0001

Focal Neurological Deficits

  

Asymptomatic (referent)

1.00

 

Symptomatic

2.7 (2.0,3.7)

<.0001

Performance Status§

  

80 (referent)

1.00

 

50

6.6 (4.4,9.9)

<.0001

Lesion Size

  

Small (referent)

1.00

 

Large

8.1 (5.3,12.4)

<.0001

Melanoma

  

NSCLC¶ (referent)

1.00

 

Melanoma

0.5 (0.4,0.6)

<.0001