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Table 2 Comparison of mean dosimetric parameters computed for 3D-CRT, TD, B-VMAT, VMAT and HT

From: Different IMRT solutions vs. 3D-Conformal Radiotherapy in early stage Hodgkin’s lymphoma: dosimetric comparison and clinical considerations

Variable Objectives 3D-CRT TD B-VMAT VMAT HT
PTV  
Volume (cm3) 428.7 ± 195.6
DMean 30 30.6±0.7b,e 30.0±0.1a,c,d 30.4±0.2b,e 30.4±0.2b,e 29.9±0.1a,c,d
V90% (%) 99 98.2±1.0b,d,e 99.2±0.7a,c,d 98.3±1.2b,e 98.6±1.1b,e 99.1±0.2a,c,d
V95% (%) 95 94.8±0.5b,d,e 97.4±1.7a,c,d,e 95.5±2.3b 95.4±1.7b 95.9±0.7a,b
V107% (%) <1 5.0±5.2b,d,e 0.02±0.03a,c,d,e 5.5±3.8b,e 5.50±3.80b,e 0.3±0.28a,b,c,d
CN95% (%) 1 0.30±0.1c,d,e 0.30±0.1c,d,e 0.67±0.1a,b,d,e 0.76±0.02a,b,c 0.77±0.06a,b,c
HI 0 0.30±0.1b,c,d,e 0.10±0.03a,c,d,e 0.20±0.1a,b,e 0.16±0.04a,b,e 0.07±0.01a,b,c,d
Lung  
Dmean(Gy) - 6.6±2.6 6.3±2.7 5.9±2.5 6.4±2.5 5.9±2.2
V5Gy (%) 50 29.3±12.4b,c,d,e 26.4±11.6a,c,d,e 31.3±14.3a,b,d,e 39.0±15.6a,b,c 37.0±12.6a,b,c
V10Gy (%) 33 22.6±9.4d 21.9±9.6d 20.8±10.0d 25.6±13.3a,b,c,e 20.6±11.0d
V15Gy (%) - 18.6±7.6c,d,e 18.5±8.2c,d,e 15.3±8.0a,b,e 15.0±10.6a,b,e 12.8±7.5a,b,c,d
V20Gy (%) - 15.2±6.2c,d,e 15.6±6.9c,d,e 11.3±6.7a,b,d,e 8.8±6.3a,b,c, 7.6±4.5a,b,c
V30Gy (%) - 3.5±2.7b,c,d,e 0.7±0.5a 0.8±0.8a 0.3±0.3a 0.1±0.3a
Breast  
Dmean(Gy) - 1.0±0.4c 0.9±0.9c 0.7±0.3a,b,d,e 0.9±0.4c 1.2±0.9 c
V4Gy (%) 50 4.5±2.3d,e 3.7±4.2d,e 4.6±3.0d,e 6.2 ±4.7a,b,c 5.4±5.5a,b,c
V10Gy (%) 33 2.5±1.4c,d,e 2.4±3.0c,d,e 1.1±1.0a,b 1.2±1.1a,b 1.4±1.8a,b
V15Gy (%) - 1.4±0.7c,d,e 1.6±2.2c,d,e 0.4±0.4a,b 0.3±0.4a,b 0.6±1.0a,b
V20Gy (%) - 0.9±0.5c,d 1.3±1.9c,d 0.1±0.1a,b 0.1±0.1a,b 0.2±0.5a,b
V30Gy (%) - 0.2±0.3c,d,e 0.6±1.0c,d,e 0a,b 0a,b 0a,b
Thyroid  
Dmean(Gy) - 17.7±4.5c,d,e 17.3±5.1c,d,e 13.5±6.3a,b 13.5±5.3a,b 14.4±5.5a,b
V18Gy (%) 50 45.9±18.1c,d,e 51.3±19.2c,d,e 35.2±21.6a,b 33.4±18.8a,b 38.2±23.0a,b
V25Gy (%) 33 32.0±14.4c,d,e 32.9±14.6c,d,e 22.2±15.8a,b 21.3±14.7a,b 24.5±19.8a,b
Coronary Ostia  
Dmean(Gy) - 22.1±9.9c,d,e 19.8±9.3c,d,e 15.7±7.9a,b 15.9±8.9a,b 16.4±8.4a,b
V20Gy (%) 100 73.5±40.8c,d,e 59.1±37.7c,d,e 43.1±32.6a,b 44.0±34.3a,b 44.3±34.2a,b
Heart  
Dmean(Gy) - 5.1±4.0c,d,e 4.3±3.7c,d,e 3.5±2.3a,b 3.1±2.2a,b 3.8±3.8a,b
Non target tissue  
Dmean(Gy) - 4.1±1.3 3.8±0.9 3.1±0.7 3.6±0.9 3.90±0.96
Time (min) - 3.2±1.1b,c,d,e 4.4±1.1a,c,d,e 12.0±2.8a,b,d,e 6.2±1.3a,b,c,e 7.2±1.6a,b,c,d
  1. Statistically significant differences (p<0.05) for each technique versus alternatives are reported: aTest vs 3D-CRT; b Test vs TD; c Test vs B-VMAT; d Test vs VMAT; e Test vs HT.