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Table 1 Relationships among HDAC1 and HDAC2 in NSCLC tissue and clinicopathologic factors

From: X-radiation inhibits histone deacetylase 1 and 2, upregulates Axin expression and induces apoptosis in non-small cell lung cancer

Clinicopathologic factor HDAC1 expression P value HDAC2 expression P value
  +   +  
Gender
 Male 38 34 0.254 39 33  
 Female 9 14 0.532 10 13 0.372
Age (years)
 < 58 26 21   28 19  
 ≥ 58 21 27 0.532 21 27 0.123
Histologic type
 SCC 22 23   25 20  
 AC 22 18   21 19  
 Others 3 7 0.366 3 7 0.339
Differentiation
 Well/Moderate 33 20   33 20  
 Poor 14 28 0.005 16 26 0.019
pTNM stage*
 I/II 34 24   35 23  
 III/IV 13 24 0.026 14 23 0.032
Lymphatic metastasis
 No 27 21   28 20  
 Yes 20 27 0.182 21 26 0.183
  1. SCC, squamous cell carcinoma; AC, adenocarcinoma.
  2. *TNM staging system of the International Union Against Cancer (2010).
  3. Pearson’s χ2 test.