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Figure 4 | Radiation Oncology

Figure 4

From: X-radiation inhibits histone deacetylase 1 and 2, upregulates Axin expression and induces apoptosis in non-small cell lung cancer

Figure 4

HDAC1, HDAC2 and Axin expression in lung carcinoma cell line after siRNA and X-radiation exposure . (A) Western blot analysis of lung carcinoma (BE1) cells after siRNA and X-radiation exposure. HDAC1 siRNA inhibited expression of HDAC1, HDAC2 siRNA inhibited expression of HDAC2 and X-radiation inhibited expression of HDAC1 and HDAC2. Both HDAC siRNA and X-radiation upregulated protein expression of Axin. (B) RT-PCR analysis of BE1 cells after siRNA and X-radiation exposure. HDAC1 siRNA inhibited expression of HDAC1, HDAC2 siRNA inhibited expression of HDAC2 and X-radiation inhibited expression of HDAC1 and HDAC2. Both HDAC siRNA and X-radiation upregulated RNA expression of Axin. HBE, human bronchial epithelial cells.

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Radiation Oncology

ISSN: 1748-717X

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