Prognostic factors for local control of stage I non-small cell lung cancer in stereotactic radiotherapy: a retrospective analysis

Table 4 Reports of stereotactic radiotherapy for stage I non-small cell lung cancer

First author (Reference No.)	Number of patients	Total dose (Gy)	Single dose (Gy/fraction)	BED₁₀ (Gy)	Median follow up (months)	Local control (%)**	3-year overall survival (%)
Timmerman[6]	55	60	20	180	34.4	98.2	55.8
Nagata[5]*	42	48	12	105.6	30	97.8	83
Fakiris[7]	70	60, 66	20, 22	180 - 211.2	50.2	94.3	42.7
Onishi[3]*	257	18 - 75	4.4 - 35	57.6 - 180	38	88.7	56.8
Our results*	80	48 - 60	4 – 12	84 – 105.6	30.4	92.5	89.9

BED₁₀ is biological effective dose (BED) calculated from prescribed dose.
* Dose is calculated at the iso-center.
**Local control (%) = (number of patients without local recurrence) / (number of all patients)×100.

ISSN: 1748-717X