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Table 4 Pre-treatment morbidity and acute and late toxicity

From: Outcome and patterns of failure after postoperative intensity modulated radiotherapy for locally advanced or high-risk oral cavity squamous cell carcinoma

  

Pre-Tx

Acute†

Late‡

Last late§

Toxicity

Grade

n (%)

n (%)

n (%)

n (%)

Pain

0

31 (59)

1 (2)

42 (80)

47 (89)

 

1

16 (30)

12 (23)

4 (7)

0

 

2

6 (11)

32 (60)

5 (9)

5 (9)

 

3

-

8 (15)

2 (4)

1 (2)

Dermatitis

0

53 (100)

-

51 (96)

53 (100)

 

1

-

14 (26)

1 (2)

-

 

2

-

30 (57)

1 (2)

-

 

3

-

9 (17)

-

-

Mucositis

0

53 (100)

-

50 (94)

53 (100)

 

1

-

7 (13)

1 (2)

-

 

2

-

27 (51)

1 (2)

-

 

3

-

19 (36)

1 (2)

-

Dysphagia

0

25 (47)

5 (9)

28 (53)

35 (66)

 

1

4 (7)

5 (9)

4 (7)

7 (14)

 

2

17 (32)

25 (48)

16 (31)

6 (11)

 

3

7 (14)

18 (34)

5 (9)

5 (9)

Xerostomia

0

53 (100)

37 (70)

34 (64)

40 (75)

 

1

-

13 (24)

15 (29)

10 (19)

 

2

-

3 (6)

4 (7)

3 (6)

 

3

-

-

-

-

Osteonecrosis

0

53 (100)

52 (98)

51 (96)

53 (100)

 

1

-

-

-

-

 

2

-

1 (2)

2 (4)

-

Highest*

0

19 (36)

-

18 (34)

30 (57)

 

1

7 (13)

4 (7)

11 (21)

11 (21)

 

2

20 (38)

14 (27)

18 (34)

7 (13)

 

3

7 (13)

35 (66)

6 (11)

5 (9)

  1. Abbreviations: Pre-Tx pre-treatment morbidity; * The highest morbidity/toxicity in a patient was counted as a single event; † During therapy and until 3 months after completion; ‡ maximal late toxicity > 3 months after completion of therapy; § Incidence of late toxicity at last follow-up visit. Percentages were rounded to reach 100% for every symptom.