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Table 4 Pre-treatment morbidity and acute and late toxicity

From: Outcome and patterns of failure after postoperative intensity modulated radiotherapy for locally advanced or high-risk oral cavity squamous cell carcinoma

   Pre-Tx Acute† Late‡ Last late§
Toxicity Grade n (%) n (%) n (%) n (%)
Pain 0 31 (59) 1 (2) 42 (80) 47 (89)
  1 16 (30) 12 (23) 4 (7) 0
  2 6 (11) 32 (60) 5 (9) 5 (9)
  3 - 8 (15) 2 (4) 1 (2)
Dermatitis 0 53 (100) - 51 (96) 53 (100)
  1 - 14 (26) 1 (2) -
  2 - 30 (57) 1 (2) -
  3 - 9 (17) - -
Mucositis 0 53 (100) - 50 (94) 53 (100)
  1 - 7 (13) 1 (2) -
  2 - 27 (51) 1 (2) -
  3 - 19 (36) 1 (2) -
Dysphagia 0 25 (47) 5 (9) 28 (53) 35 (66)
  1 4 (7) 5 (9) 4 (7) 7 (14)
  2 17 (32) 25 (48) 16 (31) 6 (11)
  3 7 (14) 18 (34) 5 (9) 5 (9)
Xerostomia 0 53 (100) 37 (70) 34 (64) 40 (75)
  1 - 13 (24) 15 (29) 10 (19)
  2 - 3 (6) 4 (7) 3 (6)
  3 - - - -
Osteonecrosis 0 53 (100) 52 (98) 51 (96) 53 (100)
  1 - - - -
  2 - 1 (2) 2 (4) -
Highest* 0 19 (36) - 18 (34) 30 (57)
  1 7 (13) 4 (7) 11 (21) 11 (21)
  2 20 (38) 14 (27) 18 (34) 7 (13)
  3 7 (13) 35 (66) 6 (11) 5 (9)
  1. Abbreviations: Pre-Tx pre-treatment morbidity; * The highest morbidity/toxicity in a patient was counted as a single event; † During therapy and until 3 months after completion; ‡ maximal late toxicity > 3 months after completion of therapy; § Incidence of late toxicity at last follow-up visit. Percentages were rounded to reach 100% for every symptom.