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Figure 5 | Radiation Oncology

Figure 5

From: Effects of ionizing radiation in combination with Erufosine on T98G glioblastoma xenograft tumours: a study in NMRI nu/nu mice

Figure 5

Effect of combination treatment on volume doubling time and tumour control. A Volume doubling time (VDT) for progression or re-growth of individual tumours after irradiation with 5 × 3.3 Gy (black circles) or without irradiation (white circles) and treatment with vehicle or 40 mg/kg BW Erufosine as indicated. Horizontal lines indicate median values of the treatment groups. B Local tumour control rates and calculated tumour control probabilities after fractionated irradiation with 5 × 3.3 Gy and graded top up doses (0–30.6 Gy) combined with injection of 40 mg/kg BW Erufosine (closed red circles) or vehicle (open black triangles). Thin lines indicate 95%-confidence intervals, size of symbols reflects number of animals (n=5-21).

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