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Table 3 Survival outcomes stratified by prognostic factors in overall and disease-free survival of patients treated for gastric cancer with or without adjuvant chemoradiotherapy

From: Adjuvant chemoradiotherapy after d2-lymphadenectomy for gastric cancer: the role of n-ratio in patient selection. results of a single cancer center

Variable

No. patients

Overall survival

P

Disease-free survival

P

 

Surgery only (n=90)

Adjuvant CT/RT (n=52)

Surgery only

Adjuvant CT/RT

 

Surgery only

Surgery CT/RT

 

Lymphatic Vessel Invasion

Yes

39

20

43.1%

65.8%

0.198

39.5%

41.7%

0.567

No

51

32

62.3%

76.8%

0.458

61.6%

68.8%

0.735

Perineural Invasion

Yes

47

20

43.7%

62.9%

0.470

40.7%

42.8%

0.787

No

43

32

64.0%

79.2%

0.222

63.1%

71.7%

0.603

Extended resection

Yes

18

8

33.3%

45.0%

0.546

33.3%

37.5%

0.951

No

72

44

59.0%

76.2%

0.219

58.5%

63.4%

0.486

Lymph node metastases

Yes

55

46

40.6%

68.2%

0.023

40.6%

53.7%

0.113

No

35

6

73.4%

100.0%

0.736

73.4%

50.0%

0.716

T-category

T1

4

7

75.0%

66.7%

0.627

75.0%

66.7%

0.627

T2

21

8

70.6%

100.0%

0.096

70.6%

71.4%

0.629

T3

5

6

25.0%

85.7%

0.081

25.0%

83.3%

0.170

T4a

55

30

51.3%

62.0%

0.875

50.1%

52.4%

0.999

T4b

5

1

20.0%

100.0%

0.259

20.0%

0.0%

0.953

N-category

N0

35

5

73.4%

100.0%

0.736

72.4%

100.0%

0.689

N1

14

10

50.0%

80.0%

0.203

50.0%

52.5%

0.674

N2

22

20

46.5%

73.1%

0.140

45.0%

64.3%

0.279

N3a

14

15

32.7%

58.7%

0.340

32.7%

41.7%

0.439

N3b

5

2

16.7%

0.0%

0.758

16.7%

0.0%

0.919

N-category – N-ratio

N0 – NR0

35

5

73.4%

100.0%

0.736

72.4%

100.0%

0.689

N1 – NR1a

5

5

80.0%

75.0%

0.688

80.0%

75.0%

0.688

N1 – NR1b

9

5

37.5%

83.3%

0.106

37.5%

40.0%

0.553

N2 – NR1

8

7

75.0%

83.3%

0.620

75.0%

85.7%

0.656

N2 – NR2 and NR3

14

13

27.8%

67.7%

0.120

26.8%

53.8%

0.251

N3a – NR2 and NR3

14

15

32.7%

58.7%

0.340

32.7%

41.7%

0.439

N3b – NR3

5

2

16.7%

0.0%

0.758

16.7%

0.0%

0.919