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Table 2 Multivariate analysis prognostic factors in overall and disease-free survival of patients treated for gastric cancer

From: Adjuvant chemoradiotherapy after d2-lymphadenectomy for gastric cancer: the role of n-ratio in patient selection. results of a single cancer center

Variable

Overall survival

Disease-free survival

 

HR (CI 95%)

P

HR (CI 95%)

P

Perineural invasion

No

1.0

 

1.0

 

Yes

2.03 (1.17-3.53)

0.011

2.46 (1.46-4.15)

0.00

Extended resection

No

1.0

 

1.0

 

Yes

2.40 (1.31-4.38)

0.004

2.58 (1.46-4,56)

0.001

Treatment modality

Surgery only

1.61 (0.85-3.04)

0.142

*

*

Adjuvant CT/RT

1.0

 

*

*

N-category – N-ratio

N0-NR0

1.0

0.021

1.0

0.008

N1-NR1a

0.72 (0.16-3.17)

0.661

0.65 (0.15-2.86)

0.568

N1-NR1b

1.92 (0.73-5.05)

0.184

2.01 (0.81-4.96)

0.131

N2-NR1

0.51 (0.14-1.81)

0.297

0.41 (0.20-1.44)

0.167

N2-NR2 and NR3

2.02 (0.93-4.39)

0.076

2.26 (1.10-4.63)

0.026

N3a – NR2 and NR3

2.78 (1.31-5.89)

0.008

2.66 (1.30-5.44)

0.007

N3b – NR3

2.96 (1.08-8.12)

0.036

2.77 (1.03-7.44)

0.043