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Table 2 Multivariate analysis prognostic factors in overall and disease-free survival of patients treated for gastric cancer

From: Adjuvant chemoradiotherapy after d2-lymphadenectomy for gastric cancer: the role of n-ratio in patient selection. results of a single cancer center

Variable Overall survival Disease-free survival
  HR (CI 95%) P HR (CI 95%) P
Perineural invasion
No 1.0   1.0  
Yes 2.03 (1.17-3.53) 0.011 2.46 (1.46-4.15) 0.00
Extended resection
No 1.0   1.0  
Yes 2.40 (1.31-4.38) 0.004 2.58 (1.46-4,56) 0.001
Treatment modality
Surgery only 1.61 (0.85-3.04) 0.142 * *
Adjuvant CT/RT 1.0   * *
N-category – N-ratio
N0-NR0 1.0 0.021 1.0 0.008
N1-NR1a 0.72 (0.16-3.17) 0.661 0.65 (0.15-2.86) 0.568
N1-NR1b 1.92 (0.73-5.05) 0.184 2.01 (0.81-4.96) 0.131
N2-NR1 0.51 (0.14-1.81) 0.297 0.41 (0.20-1.44) 0.167
N2-NR2 and NR3 2.02 (0.93-4.39) 0.076 2.26 (1.10-4.63) 0.026
N3a – NR2 and NR3 2.78 (1.31-5.89) 0.008 2.66 (1.30-5.44) 0.007
N3b – NR3 2.96 (1.08-8.12) 0.036 2.77 (1.03-7.44) 0.043