Table 1 Clinicopathological characteristics and prognostic factors in overall and disease-free survival of patients treated for gastric cancer
Variable | No. patients (n=142) | Overall survival (5-yr) | P | Disease-free survival (5-yr) | P |
|---|---|---|---|---|---|
Gender | |||||
Male | 81 | 58.7% | 0.704 | 54.1% | 0.645 |
Female | 61 | 58.9% | 57.7% | ||
Age | |||||
40 years | 10 | 70.0% | 0.321 | 60.0% | 0.450 |
41-69 years | 86 | 62.9% | 59.7% | ||
≥ 70 years | 46 | 49.6% | 47.5% | ||
Gastrectomy | |||||
Total | 80 | 49.7% | 0.024 | 43.9% | 0.007 |
Subtotal | 62 | 70.4% | 70.4% | ||
Extended resection | |||||
Yes | 26 | 35.5% | 0.004 | 34.6% | 0.002 |
No | 116 | 64.3% | 60.6% | ||
Lymphadenectomy | |||||
D1 | 13 | 50.5% | 0.270 | 47.8% | 0.388 |
D2 | 129 | 59.9% | 56.3% | ||
No. of dissected nodes | |||||
Less than 25 | 39 | 54.3% | 0.339 | 48.8% | 0.269 |
25 or more | 103 | 60.6% | 58.0% | ||
Location | |||||
Cardia | 21 | 37.0% | <0.001 | 27.7% | <0.001 |
Body | 59 | 60.3% | 57.9% | ||
Antrum | 60 | 66.8% | 64.4% | ||
Linitis | 2 | 0% | 0% | ||
Lauren histology | |||||
Intestinal | 74 | 61.4% | 0.580 | 57.1% | 0.748 |
Diffuse | 68 | 55.6% | 54.1% | ||
Lymphatic vessel invasion | |||||
Yes | 59 | 48.8% | 0.032 | 44.7% | 0.023 |
No | 83 | 66.7% | 63.8% | ||
Perineural invasion | |||||
Yes | 67 | 48.4% | 0.015 | 42.2% | 0.003 |
No | 75 | 68.9% | 68.3% | ||
T-category | |||||
T1 | 11 | 68.6% | 0.005 | 68.6% | <0.001 |
T2 | 29 | 78.4% | 71.5% | ||
T3 | 11 | 61.4% | 61.4% | ||
T4a | 85 | 53.8% | 51.2% | ||
T4b | 6 | 33.3% | 16.7% | ||
N-category | |||||
N0 | 40 | 75.8% | 0.002 | 75.8% | 0.005 |
N1 | 24 | 63.8% | 57.8% | ||
N2 | 42 | 57.7% | 53.6% | ||
N3a | 29 | 43.4% | 39.3% | ||
N3b | 7 | 14.3% | 14.3% | ||
N-ratio | |||||
NR0 | 40 | 75.8% | 0.005 | 75.8% | 0.001 |
NR1 | 39 | 69.8% | 66.3% | ||
NR2 | 27 | 43.7% | 39.9% | ||
NR3 | 26 | 36.1% | 31.0% | ||
N-category/N-ratio interaction | |||||
N0-NR0 | 40 | 75.8% | 0.002 | 75.8% | 0.001 |
N1-NR1a | 10 | 76.2% | 76.2% | ||
N1-NR1b | 14 | 57.1% | 45.7% | ||
N2-NR1 | 15 | 79.0% | 79.0% | ||
N2-NR2 and NR3 | 27 | 45.1% | 39.5% | ||
N3a-NR2 and NR3 | 29 | 43.4% | 39.3% | ||
N3b-NR3 | 7 | 14.3% | 14.3% | ||