Table 1 Baseline clinical characteristics and radiation exposure (main analysis)
Breast cancer | Prostate cancer | |
|---|---|---|
Patients with radiation to the bone, n | 207 | 213 |
Demographics | ||
Mean age, years (SD) | 65 (12.5) | 74 (8.4) |
Age, n (%) | ||
<65 years | 93 (44.9) | 31 (14.6) |
≥65 years | 114 (55.1) | 182 (85.4) |
Female, n (%) | 202 (97.6) | n/a |
Payor,* n (%) | ||
Medicare | 103 (49.8) | 133 (62.4) |
Commercial | 94 (45.4) | 64 (30.0) |
Medicaid | 7 (3.4) | 3 (1.4) |
Other | 3 (1.4) | 13 (6.1) |
Radiation profile | ||
Total REOCs, n | 220 | 233 |
Length of treatment, days | ||
Mean (SD) | 30 (16.0) | 30 (16.7) |
Median | 26 | 26 |
Dose, cGy | ||
Mean by episode | 3207 | 3301 |
Mean per patient | 3409 | 3611 |
Mean by fraction | 327 | 337 |
Radiation schedule by REOC, n | ||
Daily | 201 | 203 |
Greater than daily | 7 | 13 |
Less than daily** | 0 | 0 |
Site radiated by REOC*** n (%) | ||
Femur | 14 (6.8) | 28 (13.1) |
Hip | 45 (21.7) | 40 (18.8) |
Humerus | 3 (1.4) | 9 (4.2) |
Pelvis | 20 (9.7) | 34 (16.0) |
Rib | 12 (5.8) | 12 (5.6) |
Sacrum | 21 (10.1) | 17 (8.0) |
Skull | 9 (4.3) | 10 (4.7) |
Spine | 97 (46.9) | 95 (44.6) |
Other bone sites | 28 (13.5) | 27 (12.7) |
Total fractions | 2173 | 2344 |
Fractions by REOC | ||
Mean (SD) | 9 (5) | 10 (4) |
Median | 10 | 10 |
Fractionation schedule,† n | ||
1 | 9 | 10 |
4 to 5 | 21 | 23 |
10 | 35 | 43 |
15 | 47 | 47 |
Other | 102 | 96 |
Fractions by site,‡ n | ||
Femur | 10.2 | 9.7 |
Hip | 10.0 | 9.6 |
Humerus | 9.0 | 10.3 |
Pelvis | 8.7 | 8.1 |
Rib | 9.4 | 5.0 |
Sacrum | 10.6 | 10.9 |
Skull | 11.3 | 10.5 |
Spine | 9.9 | 10.2 |
Other bone site | 8.8 | 10.4 |